Peritoneal Malignant Mesothelioma Metastasizing to Lymph Node in Young Male-a Case Report. in Indian journal of surgical oncology / Indian J Surg Oncol. 2024 Mar;15(1):145-148. doi: 10.1007/s13193-023-01838-1. Epub 2023 Oct 19.

2024

Tipo pubblicazione

Case Reports;

Autori/Collaboratori (6)Vedi tutti...

Singh A
Department of Pathology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab India. GRID: grid.427691.f. ISNI: 0000 0004 1799 5307
Bansal C
Department of Pathology, Dr SS Tantia Medical College, Hospital, & Research Center, Sri Ganganagar, Rajasthan India.
Singla D
Department of Pathology, Dr SS Tantia Medical College, Hospital, & Research Center, Sri Ganganagar, Rajasthan India.

et alii...

Abstract

Peritoneal malignant mesothelioma is an uncommon neoplasm with a poor prognosis. We hereby report a case of a 20-year-old male, first diagnosed on biopsy with axillary lymph node metastasis. He presented with abdominal pain and axillary lymphadenopathy, with no history of asbestos exposure. CECT showed peritoneal thickening and ascites. Ascitic fluid cytology showed reactive morphology. The diagnosis of metastatic deposits of malignant mesothelioma was made on histopathology and confirmed by immunohistochemistry. Tumor cells were immune-reactive for CK 5/6, calretinin, D2-40, and WT1 and negative for TTF1, CK 20, and CD 3. This case report has two important highlights-(i) unusual presentation with axillary lymph node metastasis leading to diagnostic dilemma in a young male with no asbestos exposure history and (ii) confirmatory diagnostic role of IHC in Peritoneal malignant mesothelioma.

PMID : 38511037

DOI : 10.1007/s13193-023-01838-1