Global, regional, and national burden of ovarian cancer among young women during 1990-2019. in European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) / Eur J Cancer Prev. 2025 Jan 1;34(1):1-10. doi: 10.1097/CEJ.0000000000000899. Epub 2024 Jun 4.

2025

Tipo pubblicazione

Journal Article;

Autori/Collaboratori (7)Elenco ridotto...

Liu J
The Second Clinical Medical School, Nanjing Medical University, Nanjing, China.
Qu L
The Second Affiliated Hospital, Nanjing Medical University.
Wu C
The Second Affiliated Hospital, Nanjing Medical University.
Chen J
The Second Affiliated Hospital, Nanjing Medical University.
Tang Z
The Second Clinical Medical School, Nanjing Medical University, Nanjing, China.
Gu G
The Second Clinical Medical School, Nanjing Medical University, Nanjing, China.
Zhuang Q
The Second Affiliated Hospital, Nanjing Medical University.

Abstract

BACKGROUND: Ovarian cancer, the most devastating tumor in women globally, significantly impacts young women, compromising their daily lives and overall well-being. Ovarian cancer represents a significant public health concern due to its extensive physical and psychological consequences. MATERIAL AND METHODS: Data from the Global Burden of Disease were used to assess the global, regional, and national burden of ovarian cancer in young women aged 20-39 from 1990 to 2019. This analysis focused on trends measured by the estimated annual percentage change and explored the socioeconomic impacts via the socio-demographic index (SDI). RESULTS: During 1990-2019, the incidence and prevalence of ovarian cancer among young women increased globally, with annual rates of 0.74% and 0.89%, respectively. The mortality rate and disability-adjusted life years also rose annually by 0.20% and 0.23%, respectively. A significant burden shift was observed toward regions with lower SDI, with high fasting plasma glucose, BMI, and asbestos exposure identified as prominent risk factors, particularly in lower SDI regions. CONCLUSION: Our findings underscore ovarian cancer in young women as an escalating global health challenge, with the burden increasingly shifting toward lower socioeconomic areas. This underscores the necessity for targeted prevention and control strategies for ovarian cancer, focusing on reducing the identified risk factors and ensuring equitable health resource distribution.

PMID : 38837195

DOI : 10.1097/CEJ.0000000000000899

Keywords

Cost of Illness; Socioeconomic Factors; Disability-Adjusted Life Years/trends; Risk Factors; Global Health/statistics & numerical data; Prevalence; Incidence; Global Burden of Disease/trends; Adult; Young Adult; Ovarian Neoplasms/epidemiology; Female; Humans;